Research Study
Effect of sinus mucus transfer to deplete sinus disease causing bacteria.
Can a microbiota transfer cure CRS?
Draft
Health Areas
Complementary/ Alternative Medicine, Transplantation, Other Diagnosis and Therapy, Sinusitis, Other Ear, Nose, Mouth and Throat
Study Purpose
The lack of effective recalcitrant chronic rhinosinusitis (CRS) therapies has led us to test whether a SinoNasal Microbiota Transfer (SNMT) can trigger CRS recovery. A sinonasal microbiota transfer may eliminate sinus pathogens and restore the sinus microbiota to a healthy state. The goal is to assess whether SNMT will decolonize and reconstitute the microbiota of CRS patients, thereby preventing the recurrence of sinus infections.
Details
If you are eligible after the screening phase, you will undergo the SNMT procedure over 2 consecutive days. After the procedure, there are 4 study visits where your health and condition will be assessed. Study visits include questionnaires, a nasal endoscopy, culture work, blood work, and other measurements.
location
Vancouver Island / Coast
Lower Mainland
Thompson - Okanagan
Kootenay
Cariboo
North Coast and Nechako
Northeast
recruitment end date
1969-10-01
eligibility
Age: 19 Years - 99 Years Old
Accepting Healthy Volunteers: Yes
Research Team Information
Principal investigator
Amee Manges
health authority affiliation
Vancouver Coastal Health
academic affiliation
University of British Columbia - Vancouver
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